VAINSTEIN, ALEXANDER,MARTON, IRA,HONIG, ARIK,MARHEVKA, ELENA
申请号：
CA2968808
公开号：
CA2968808A1
申请日:
2015.11.26
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
A nucleic acid construct is provided. The construct comprises a tobacco rattle virus (TRV) sequence and a nucleic acid sequence encoding a single guide RNA (sgRNA) that mediates sequence-specific cleavage in a target sequence of a genome of interest, wherein the TRV sequence is devoid of a functional 2b sequence. Also provided are plant cells comprising the construct and uses of the construct in gene editing.
