The present invention relates to novel activatable particles which can be used in the health field. More specifically, the invention relates to composite particles comprising an intracellular targeting element, which can generate a response when excited, and to the uses thereof in the health field, particularly in relation to human health. The inventive particles comprise a nucleus comprising at least one inorganic and optionally one or more other organic compound(s) and which can be activated in vivo, in order to label or alter cells, tissues or organs. The invention also relates to methods for producing such particles, as well as pharmaceutical and diagnostic compositions containing same.
