BIODISTRIBUTION AMÉLIORÉE D'OLIGOMÈRES

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专利权人:

GROOVE BIOPHARMA CORPORATION

发明人:

MCELLIGOTT, DAVID L.

申请号：

EP12752665

公开号：

EP2681336A4

申请日:

2012.03.02

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

This invention relates generally to oligomers useful for modulating expression and/or activity of RNAs or genes. More particularly, the invention relates to single stranded, double stranded, partially double stranded and hairpin structured chemically modified oligomers that have a broad biodistribution profile for inhibiting RNA expression in a plurality of cells, tissues, or organs, and to methods of making and using the modified oligomers.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/