This invention concerns a measuring system for the calculation of dimensions, including area and volume, of objects in various shapes. In particular, it concerns miniature 3D measuring equipment that is perfectly suitable for 3D measurements of subcutaneous tumors in mice. The primary objective of this invention then also consists of a measuring system for 3D measurements of objects in various shapes, which includes a handheld device that has at least 1 camera, 1 projector and a measuring chamber. In another implementation, the handheld device will have 2 cameras and a projector and the 3D measurement is based on stereo-vision. Another objective is directed to ensuring that said handheld device also has a processor module, a user interface, a power supply, a data communication interface, and exchangeable measuring chambers which provide the flexibility and autonomy to speed up the measurement procedure, and significantly improve the reproducibility of the measurement.