Jason Baum,Bryan Johnson,Alexey Alexandrovich Lugovskoy,Lihui Xu,Neeraj Kohli,Jonathan Basil Fitzgerald,Sharlene Adams
申请号:
US13451135
公开号:
US08476409B2
申请日:
2012.04.19
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Provided are bispecific antibodies that are useful as anti-neoplastic agents and that bind specifically to human IGF-1R and human ErbB3. Exemplary antibodies inhibit signal transduction through either or both of IGF-1R and ErbB3.