The present invention relates to pharmaceutical use of c-Met specific drug containing quinoline ring and preparation method thereof. Specifically, the invention relates to the use of a compound of formula (I) in the preparation of a medicament for the treatment of cancer caused by gene amplification of c-Met. The compound of formula (I) has a strong inhibitory effect and high selectivity to cancers caused by gene amplification of c-Met.本發明涉及含有喹啉環的c-Met特異性藥物的製藥用途及其製備方法。具體涉及式(I)化合物在製備用於治療由c-Met基因擴增引起的癌症的藥物中的用途。式(I)化合物對因c-Met基因擴增引起的癌症具有很強的抑制作用和選擇性。本案圖式皆為結果數據,故本案無指定代表圖。