芸香苷、牡丹酚及銀杏內酯A用於製備抑制或延緩NMDA 受體過度活化之藥物的用途农业专利-农业学术服务平台

发明人:: LIN, YEN-SHOU,林炎寿,林炎壽,TSAI, HAN-JUNG,蔡涵容,蔡涵容,LIN, TIAN-XUAN,林恬瑄,林恬瑄,KUO, LI-CHEN,郭力祯,郭力禎,LEE, CHIH-HAN,李智翰,李智翰

摘要：: The present invention discloses a use of receptor antagonists for manufacturing drugs of preventing, treating, inhibiting, delaying diseases of hyper-activation of NMDA receptor or AMPA receptor, in which the NMDA receptor antagonist is selected from a group consisting of paeonol, baicalein, rutin and ginkgolide A, and the AMPA receptor antagonist is baicalein.本發明係關於一種NMDA受體或AMPA受體拮抗劑的用途，用於製備預防、治療、抑制或延緩因NMDA受體或AMPA受體過度活化之疾病的藥物，其中NMDA受體拮抗劑係選自於由牡丹酚(Paeonol)、黃芩素(Baicalein)、芸香苷(Rutin)、銀杏內酯(Ginkgolide A)及其組合所組成之群組，且AMPA受體拮抗劑係為黃芩素(Baicalein)。