Marc S. PENN,Rahul ARAS,Joseph PASTORE,Timothy J. MILLER
申请号：
US15305369
公开号：
US20170049856A1
申请日:
2015.04.28
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Provided herein are methods of treating a cardiomyopathy in a subject by administering directly to, or expressing locally in, a weakened, ischemic, and/or peri-infarct region of myocardial tissue of the subject an amount of SDF-1 effective to cause functional improvement in at least one of the following parameters: left ventricular volume, left ventricular area, left ventricular dimension, cardiac function, 6-minute walk test, or New York Heart Association (NYHA) functional classification. Methods of treating subjects with advanced ischemic cardiomyopathy are further disclosed herein.
