INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY
发明人:
PARK, Chang Hwan,박장환,LEE, Eun Hye,이은혜
申请号:
KRKR2016/006608
公开号:
WO2017/003125A1
申请日:
2016.06.22
申请国别(地区):
WO
年份:
2017
代理人:
摘要:
The present invention provides a composition for preventing, alleviating, or treating cranial nerve diseases caused by dopamine deficiency, the composition containing triiodidethyronine and tyroxine, or a salt thereof. According to the present invention, the triiodidethyronine and tyroxine, or a salt thereof significantly promote the expression and proliferation of dopamine neurons, thereby exhibiting excellent effects in the prevention and treatment of cranial nerve diseases caused by dopamine deficiency, such as Parkinson´s disease.La présente invention concerne une composition pour prévenir, soulager, ou traiter des maladies des nerfs crâniens provoquées par une carence en dopamine, ladite composition contenant de la triiodidethyronine et de la thyroxine, ou leur sel. Selon la présente invention, la triiodidethyronine et la thyroxine, ou leur sel, favorisent considérablement lexpression et la prolifération de neurones de la dopamine, et présentent ainsi dexcellents effets dans la prévention et le traitement de maladies des nerfs crâniens provoquées par une carence en dopamine, telles que la maladie de Parkinson.본 발명은 트리요오드티로닌과 티록신, 또는 이의 염을 포함하는 도파민 결핍으로 인한 뇌신경계 질환의 예방, 개선 또는 치료용 조성물을 제공한다. 본 발명에 따르면, 트리요오드티로닌과 티록신, 또는 이의 염은 도파민 뉴런의 발현 및 증식을 현저하게 증진시킴으로써 파킨슨병과 같은 도파민 결핍으로 인한 뇌신경계 질환의 예방 및 치료에 뛰어난 효과를 나타낸다.