BRYCH, STEPHEN ROBERT,WONG, LYANNE M.,FALLON, JAYMILLE,GOSS, MONICA MICHELLE,GU, JIAN HUA,GHATTYVENKATAKRISHNA, PAVAN K.
申请号：
CA3054165
公开号：
CA3054165A1
申请日:
2018.04.27
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Disclosed herein are aqueous pharmaceutical formulations comprising denosumab or another human anti-RANKL monoclonal antibody or portion thereof, and characteristics of pH, buffer systems, and amino acid aggregation inhibitors. Also disclosed are presentation of the formulation for use, e.g. in a single-use vial, single-use syringe, or glass container, methods of using the formulations and articles for preventing or treating diseases, and related kits.
