GARY A. ROGERS,LESLIE STREET,RUDOLF MUELLER,STAN RACHWAL,SEAN M. O'HARE,STEPHEN LEE
申请号：
BRPI0720323
公开号：
BRPI0720323A2
申请日:
2007.12.28
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
This invention relates to the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for higher order behaviors. These brain networks are involved in cognitive abilities related to memory impairment, such as is observed in a variety of dementias and in imbalances in neuronal activity between different brain regions, as is suggested in disorders such as Parkinson's disease, schizophrenia and affective disorders. In a particular aspect, the present invention relates to compounds useful for treatment of such conditions, and methods of using these compounds for such treatment.
