Hughes, Adam,Fenster, Erik,Fleury, Melissa,Gendron, Roland,Moran, Edmund J.
申请号:
HRP20170646
公开号:
HRP20170646T1
申请日:
2017.04.25
申请国别(地区):
HR
年份:
2017
代理人:
摘要:
In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, and Z are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.