An oral detection device is used for making oral detection of gastroesophageal reflux disease or other diseases or disorders. It includes a sensor, a sensor container, a base and a tooth retainer. The sensor is held in the sensor container and got its orientation maintained towards the esophageal opening. The tooth retainer works to connect the base where the sensor container and the sensor within are secured to, to teeth in either a maxillary style or a mandibular style. In this way, the oral detection device is able to detect gastroesophageal reflux or other targets in mouth in a removable and reusable way.
