REDUCTION PAR INHIBITEUR DE C5AR DU TAUX URINAIRE DE SCD163

• 收藏
• 分享

专利权人:

INC.;CHEMOCENTRYX

发明人:

DENG, JUN,SCHALL, THOMAS J.,BEKKER, PETRUS

申请号：

CA3078732

公开号：

CA3078732A1

申请日:

2018.10.30

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

Provided herein are methods of treating ANCA-associated vasculitis (AAV) in individuals in need thereof comprising administering a complement component 5a receptor (C5aR) antagonist. Also provided herein are methods of treating a ANCA-associated vasculitis (AAV) with renal involvement in an individual in need thereof comprising administering a complement component 5a receptor (C5aR) antagonist to the individual if the individual exhibits an elevated urinary soluble CD163 (sCD163) to creatinine ratio compared to individuals without AAV. In some embodiments, the complement component 5a receptor (C5aR) antagonist is avacopan.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/