substituted pyrazole quinazoline derivatives as kinase inhibitors

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专利权人:

NERVIANO MEDICAL SCIENCES S.R.L

发明人:

ANTONELLA ERMOLI,CLAUDIA PIUTTI,DANIELA FAIARDI,FRANCESCO CASUSCELLI

申请号：

BR112013008527

公开号：

BR112013008527A2

申请日:

2011.12.16

申请国别(地区):

BR

年份:

2016

代理人:

摘要：

The present invention relates to substituted pyrazolo[4,3-h]quinazoline compounds which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular PIM kinases. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such these compounds or the pharmaceutical compositions containing them.

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