Compounds are disclosed herein comprising or a pharmaceutically acceptable salt, or a metabolite or a prodrug thereof； wherein a dashed line indicates the presence or absence of a bond； Y, A, and B are described herein Therapeutic methods, manufacturing methods, compositions, and medicaments related thereto are also disclosed.本文所揭示化合物包括：或其一醫藥上可接受之鹽、或代謝產物或前藥；其中虛線表示存在或不存在一鍵結；Y、A及B闡述於本文中。本文亦揭示與其相關之治療方法、製造方法、組合物及藥物。
