Compositions including an odd chain fatty acid, and salts and derivatives thereof, and methods for metabolic syndrome treatment and prophylaxis are provided, including compositions and methods for treating diabetes, obesity, hyperferritinemia, elevated insulin, glucose intolerance, dyslipidemia and related conditions. Methods for the diagnosis and monitoring of metabolic syndrome are also provided.本發明提供包括奇數碳鏈脂肪酸的組合物及其鹽及衍生物及代謝症候群治療及預防方法,包括用於治療糖尿病、肥胖、高鐵蛋白血症、胰島素升高、葡萄糖不耐、血脂異常及相關病狀之組合物及方法。亦提供用於診斷及監測代謝症候群之方法。