immunogenic molecule, composition, method of treating or preventing a condition caused or associated with plasmodium falciparum infection and screening for the presence of an antibody inhibiting plasmodium falciparum invasion in a patient； and, use of an immunogenic molecule and a composition
THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH
发明人:
ALAN COWMAN,JACOB BAUM,LIN CHEN
申请号：
BRPI0917331
公开号：
BRPI0917331A2
申请日:
2009.08.27
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
This invention relates to an immunogenic molecule comprising a contiguous amino acid sequence of an invasion ligand of a strain of Plasmodium falciparum, the invasion ligand capable of binding to an erythrocyte receptor, the receptor function being resistant to trypsin and neuraminidase and chymotrypsin, wherein when administered to a subject the molecule is capable of inducing an immune response to the strain. The invention further relates to compositions and methods for the treatment of diseases such as malaria.
