The invention relates to a system for performing an anastomosis between an organic wall having an opening and an organic hollow tube, comprising:a body inserted inside the tube and through the openingexternal clamping elements defining with said body a tubular portion on the wall and forming an anchoring clampa device for connecting said tube and said tubular portion, comprising: suture elements connecting the external clamping elements to the body and each having a first end connected to a tightening device and a second end adapted for being retained on an external clamping element anda suturing device adapted for moving the second end of the suture elements between a retracted configuration where it is located inside the tube, and an anchored configuration where it is retained on an external clamping element after passing through the tube.