ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
发明人:
WILLIAMS, STUART K.,HOYING, JAMES B.
申请号：
CA2610646
公开号：
CA2610646C
申请日:
2006.06.02
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The present invention provides an implantable devices for providing abiologically active agent to a subject in need thereof, the device comprisinga microvessel construct in contact with a biocompatible, semi-permeable pouch,the pouch encapsulating a cell or cells capable of producing the biologicallyactive agent. The present invention also provides methods for treating orpreventing a disorder in a subject using the implantable device. The presentinvention also provides specific methods for treating or preventing diabetesin a subject comprising implanting in the subject an immunoisolation devicecomprising a microvessel construct in contact with a biocompatible, semi-permeable pouch, the pouch encapsulating a cell or cells capable of producinga therapeutically effective amount of insulin. Methods for vascularizing andrevascularizing tissue, including engineered tissue, are also provided.
