Stichting Katholieke Universiteit; more particularly The University Medical Centre Nijmegen
发明人:
Marion J. G. Bussemakers,William B. Isaacs
申请号：
US14033699
公开号：
US09540696B2
申请日:
2013.09.23
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates, in general, to a prostate-specific antigen, PCA3. In particular, the present invention relates to nucleic acid molecules coding for the PCA3 protein； purified PCA3 proteins and polypeptides； recombinant nucleic acid molecules； cells containing the recombinant nucleic acid molecules； antibodies having binding affinity specifically to PCA3 proteins and polypeptides； hybridomas containing the antibodies； nucleic acid probes for the detection of nucleic acids encoding PCA3 proteins； a method of detecting nucleic acids encoding PCA3 proteins or polypeptides in a sample； kits containing nucleic acid probes or antibodies； bioassays using the nucleic acid sequence, protein or antibodies of this invention to diagnose, assess, or prognose a mammal afflicted with prostate cancer； therapeutic uses； and methods of preventing prostate cancer in an animal.
