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Amino-substituted imidazopyridazines
专利权人:
Bayer Intellectual Property GmbH
发明人:
EIS, Knut,PÜHLER, Florian,ZORN, Ludwig,LIENAU, Philip,SUELZLE, Detlev,HÄGEBARTH, Andrea,BÖMER, Ulf,PETERSEN, Kirstin,SCHULZE, Volker
申请号:
ES12806400
公开号:
ES2650915T3
申请日:
2012.12.10
申请国别(地区):
ES
年份:
2018
代理人:
摘要:
A compound of general formula (I): ** Formula ** in which: ** Formula ** represents a group selected from: ** Formula ** in which * indicates the point of attachment of said groups with the rest of the molecule; R1 represents a linear C2-C6-alkyl group, a branched C3-C6-alkyl group or a C3-C6-cycloalkyl group which is optionally substituted with one or more substituents selected independently from each other from: a halogen atom, a group -CN, C1-C6- alkyl, C1-C6- haloalkyl, C2-C6- alkenyl, C2-C6- alkynyl, C3-C10- cycloalkyl, 3- to 6-membered heterocycloalkyl which is spirolated; arylo optionally substituted one or more times, independently of each other, with a substituent R; aryl-C1-C6 alkyloxy- optionally substituted one or more times, independently of each other, with a substituent R; heteroaryl- optionally substituted one or more times, independently of each other, with a substituent R; -C (>; = O) NH2, -C (>; = O) N (H) R ', -C (>; = O) N (R') R ", -C (>; = O) OH, -C ( >; = O) OR ', -NH2, -NHR', -N (R ') R ", -N (H) C (>; = O) R', -N (R ') C (>; = O) R ', -OH, C1-C6 alkoxy-, halo C1-C6-, -OC (>; = O) R', -OC (>; = O) NH2, -OC (>; = O) NHR ', -OC (>; = O) N (R ') R ", -SH, C1-C6-S-alkyl-; R2 represents a hydrogen atom; R3 represents a substituent selected from: a halogen atom, a group -CN, C1-C6 alkyl -, C1-C6- haloalkyl, C2-C6- alkenyl, C2-C6- alkynyl, -C (>; = O) R ', -C (>; = O) NH2, -C (>; = O) N (H) R ', -C (>; = O) N (R') R ", -NH2, -NHR ', -N (R') R", -N (H) C (>; = O) R ', -N (R) C (>; = O) R ', -N (H) C (>; = O) NH2, -N (H) C (>; = O) NHR', -N (H) C (>; = O) N (R ') R ", -N (R') C (>; = O) NH2, -N (R ') C (>; = O) NHR', -N (R ') C (>; = O) N (R ') R ", -N (H) C (>; = O) OR', -N (R ') C (>; = O) OR', -NO2, -N (H) S (>; = O) R ', -N (R') S (>; = O) R ', -N (H) S (>; = O) 2R', -N (R ') S (>; = O) 2R', -N>; = S (>; = O) (R ') R ", -OH, C1-C6-alkoxy-, halo-C1-C6-alkoxy, C3-C6-cycloalkoxy, C3-C6-cy
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