Steward, Michael W.,Person, Roland H.,Griffith, Irwin J.,Tiege, Paul B.,Noujaim, Antoine A.
申请号:
AU2015200603
公开号:
AU2015200603B2
申请日:
2015.02.06
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
#$%^&*AU2015200603B220170223.pdf#####ABSTRACT The present invention relates generally to methods and compositions for targeting and delivering solid-phase platelet-dependent vascular occlusion agents. In particular, particles or coils or stents coated with platelet binding agents are directed to target vasculature, such as the vasculature of solid tumor masses or AV-malformations or aneurysms or endoleaks the solid-phase agent then binds and activates platelets, which in turn bind and activate other platelets. This process results in the rapid formation of a platelet-mediated thrombus about the solid-phase agent causing vessel occlusion