Frank J. Massino;Ludek Frohich;Karel Dolezal;Miroslav Stmad;Marek Zatioukai;Lucie Szucova;Lukas Spichal
发明人:
Lucie Szucova,Marek Zatioukai,Lukas Spichal,Ludek Frohich,Karel Dolezal,Miroslav Stmad,Frank J. Massino
申请号：
US13630673
公开号：
US20130072505A1
申请日:
2012.09.28
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides methods and compositions for countering the adverse effects of aging on mammalian cells in vitro and in vivo, especially human skin cells and human skin, and treatment of hyperproliferative and related skin diseases in mammals by administering compositions containing 6,9-disubstituted purine derivatives.
