Jason Robert Gotlib,Garry P. Nolan,James L. Zehnder,Stephen Tracy Oh
申请号：
US13005455
公开号：
US20120046233A1
申请日:
2011.01.12
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Aspects of the present invention include methods, compositions and kits for classifying a subject as having or being predisposed to a hematolymphoid neoplasm or malignancy if they harbor a mutation in the LNK gene. Aspects of the present invention also include screening for candidate agents for treating LNK mutation-based hematolymphoid neoplasms or malignancies in cell-based and cell free assays as well as therapeutic compositions for treating a LNK-mutant based hematolymphoid disorder. Also provided are compositions, systems, kits and computer program products that find use in practicing the subject methods.
