DISPOSITIF A MICRO-AIGUILLE COMPRENANT UN AGENT THERAPEUTIQUE PEPTIDIQUE ET UN ACIDE AMINE ET PROCEDES DE FABRICATION ET D'UTILISATION DE CELUI-CI

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专利权人:

3M INNOVATIVE PROPERTIES COMPANY

发明人:

ZHANG, YING,FENN, PERCY T.,JOHNSON, PETER R.

申请号：

CA2857501

公开号：

CA2857501A1

申请日:

2012.11.30

申请国别(地区):

CA

年份:

2013

代理人:

摘要：

A medical device including an array of microneedles and a coating disposed on or within the microneedles and a method of making such a device are disclosed. The coating includes a peptide therapeutic agent and an amino acid. A method of stabilizing a peptide therapeutic agent with an amino acid on an array of microneedles is also disclosed. In some cases, the peptide therapeutic agent and the amino acid either both have a net positive charge or both have a net negative charge. In some cases, the peptide therapeutic agent is histidine.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/