Pradip Mukerji;Tapas Das;Jennifer Thurmond;Suzette L. Pereira;Yung-Sheng Huang
发明人:
Pradip Mukerji,Tapas Das,Yung-Sheng Huang,Jennifer Thurmond,Suzette L. Pereira
申请号：
US12878788
公开号：
US08143486B2
申请日:
2010.09.09
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., “Δ5-desaturase”) and at carbon 6 (i.e., “Δ6-desaturase”) and to uses thereof. In particular, Δ5-desaturase may be utilized, for example, in the conversion of dihomo-γ-linolenic acid (DGLA) to arachidonic acid (AA) and in the conversion of 20:4n-3 to eicosapentaenoic acid (EPA). Delta-6 desaturase may be used, for example, in the conversion of linoleic (LA) to γ-linolenic acid (GLA). AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
