Pan, Jingwen,Grier, Mark,Assefa, Haregewein,Ismail, Mohamed,Verma, Atul,Abato, Paul,Bowser, Todd,Bhatia, Beena,Kim, Oak K.,Nelson, Mark,Honeyman, Laura,Berniac, Joel
申请号:
AU2007338747
公开号:
AU2007338747B2
申请日:
2007.12.21
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention pertains, at least in part, to a substituted tetracyclinecompound of Formula (I): wherein X is CHC(R13VY), CR6 R6, C=CR6 R6, S, NR6, or O;E is NR7dR7β, OR7f or (CH2)o.iC(=W)WR7s; W is O, S, NR711 or CR75R7*; W isO, S or NR7*; These tetracycline compounds can be used to treat numerous tetracyclinecompound-responsive states, such as bacterial infections and neoplasms.