YAO, WENQING,姚文清,HE, CHUNHONG,何春红,何春紅,ZHUO, JINCONG,卓金聪,卓金聰,XU, MEIZHONG,徐美忠,ZHANG, COLIN,张丰雷,張豐雷,QIAN, DING-QUAN,钱定权,錢定權,BURNS, DAVID M.,大卫Ｍ 伯斯,大衛Ｍ 伯斯,METCALF, BRIAN W.,布莱恩Ｗ 梅特凯夫,布萊恩Ｗ 梅特凱夫,大卫M 伯斯,大衛M 伯斯,布莱恩W 梅特凯夫,布萊恩W 梅特凱夫
申请号：
TW094139285
公开号：
TWI400239B
申请日:
2005.11.09
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.本發明係關於11-β羥基固醇脫氫酶1型之抑制劑，礦物皮質醇受體(MR)之拮抗劑及其醫藥組合物。本發明化合物可用於治療與11-β羥基固醇脫氫酶1型之表現或活性有關之各種疾病及/或與醛固酮過量有關之疾病。
