The present invention provides a way to increase the hatchability of poultry eggs, by applying a specific regime for the vaccination against avian Reovirus. It was found that the administration to poultry of an inactivated avian Reovirus vaccine, at least two times, prior to onset of lay, can lead to a production of 4 to 5 more chicks per breeder hen, over one egg-laying period. This advantageous effect can be obtained through the vaccinations, methods, and uses as defined herein.
