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Indazolyl derivatives useful as potassium channel modulating agents
- 专利权人:
- Charlotte Hougaard;Tina Holm Johansen;Ulrik Svane Sørensen;Birgitte L. Eriksen;Lene Teuber;Palle Christophersen;Dan Peters
- 发明人:
- Birgitte L. Eriksen,Ulrik Svane Sørensen,Charlotte Hougaard,Lene Teuber,Dan Peters,Palle Christophersen,Tina Holm Johansen
- 申请号：
- US12444344
- 公开号：
- US08222262B2
- 申请日:
- 2007.10.03
- 申请国别(地区):
- US
- 年份:
- 2012
- 代理人:
- 摘要：
- Potassium channel modulating agents of Formula Ia or Iband enantiomers and mixtures enantiomers and N-oxides thereof, and pharmaceutically acceptable salts thereof, and their use in the preparation of pharmaceutical compositions. Also, pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the activity of potassium channels, e.g., respiratory diseases, epilepsy, convulsions, vascular spasms, coronary artery spasms, renal disorders, polycystic kidney disease, bladder spasms, urinary incontinence, bladder outflow obstruction, irritable bowel syndrome, gastrointestinal dysfunction, secretory diarrhoea, ischaemia, cerebral ischaemia, ischaemic heart disease, angina pectoris, coronary heart disease, traumatic brain injury, psychosis, schizophrenia, anxiety, depression, dementia, memory and attention deficits, Alzheimer's disease, dysmenorrhea, narcolepsy, Reynaud's disease, intermittent claudication, Sjorgren's syndrome, migraine, arrhythmia, hypertension, absence seizures, myotonic muscle dystrophia, xerostomi, diabetes type II, hyperinsulinemia, premature labor, baldness, cancer, immune suppression, or pain.
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
