PROBLEM TO BE SOLVED: To provide a nanofiber laminate sheet capable of performing skin care and makeup at the same time when used as a cosmetic sheet.SOLUTION: The nanofiber laminate sheet comprises a layer of nanofibers composed of a water-insoluble polymeric compound and a layer of a water-soluble polymeric compound containing a cosmetic component or a medicinal component. Preferably, the nanofibers are colored. Preferably, the layer of the water-soluble polymeric compound comprises a layer of nanofibers composed of a water-soluble polymeric compound containing the active ingredient.