REPUBLIC OF KOREA(ANIMAL AND PLANT QUARANTINE AGENCY)
发明人:
BYUN, JAE WONKR,변재원,KIM, JONG WANKR,김종완,KIM, HA YOUNGKR,김하영,CHAE, MYEONG JUKR,채명주,LEE, WAN KYUKR,이완규,CHOI, HWAN WONKR,최환원,HONG, SEONG KEUNKR,홍성근,YOON, IN JOONGKR,윤인중
申请号：
KR1020150077810
公开号：
KR1020160142023A
申请日:
2015.06.02
申请国别(地区):
KR
年份:
2016
代理人:
摘要：
The present invention relates to a method for isolating shiga toxin-producing E.coli from swine, secreting shiga toxin 2e variant (STX2e) in swine with edema disease, using the E.coli as a vaccine strain, and producing a large amount of STX2e secreted from the vaccine strain, and relates to a vaccine for preventing edema disease of swine containing inactivated toxoid by inactivating the vaccine strain. Therefore, the present invention can reduce damage to farms by preventing edema disease of swine.COPYRIGHT KIPO 2016본 발명은 부종병에 이환된 돼지에서 시가독소(shigatoxin 2e variant)를 분비하는 시가독소 산생 대장균(Shigatoxin producing E. coli)을 돼지에서 분리한 후 백신주로 이용하고, 상기 백신주가 분비하는 부종병 독소(STX2e)를 대량으로 생산하는 방법 및 상기 백신주를 불활화하여 무독화된 톡소이드를 함유하는 돼지 부종병 예방용 백신에 관한 것이다.
