The present invention generally provides methods and devicesfor removing fluid from a surgical instrument. Surgical access devicesand seal systems are generally provided having one or more valves or sealassembliesto create a closed system between the outside environment and theenvironment in which the surgical access device is being inserted. The devicesof systems can also include a fluid remover in the form of a sorbent element,a scraper element, a wicking element, or any combination thereof thatis configured to remove fluid from a working channel of the device or systemand/or from a surgical instrument inserted therethrough.