Lei Xiao,Chengfei Pu,Zhiyuan Cao,He Sun,Mao Bi,Zhao Wu
申请号：
US15942112
公开号：
US20180222995A1
申请日:
2018.03.30
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present disclosure relates to compositions and methods for compositions, methods, and kits for treating cancer using chimeric antigen receptor (CAR) modified cells. Some embodiments of the present disclosure relate to an isolated nucleic acid sequence encoding CAR. The CAR may include an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain. The antigen binding domain may bind to an antigen of a non-essential organ.
