USES OF CIMIRACEMATE A AND RELATED COMPOUNDS FOR TREATING INFLAMMATION AND MODULATING IMMUNE RESPONSES

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专利权人:

Cindy Lai Hung Yang;Allan Sik Yin Lau

发明人:

Allan Sik Yin Lau,Cindy Lai Hung Yang

申请号：

US13812265

公开号：

US20130324605A1

申请日:

2011.07.29

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The present invention pertains to Cimiracemate A and related compounds that are useful as inhibitors of 5-lipoxygenase (5-1. OX) activity and various proinflammatory mediators such as lipoxins, leukotrienes (e.g., LTA4, LTB4, LTC4, LTD4, and LTE4), prostaglandins, and thromboxanes. The present invention also provides therapeutic methods and compositions for treatment of inflammation and inflammatory conditions, including allergenic reactions, diseases associated with cell proliferation, neoangiogenesis, and cardiovascular diseases.

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