The invention is a new dispensing device for pressurized containers (C) of coolantsfor cryotherapy, with manual opening/closing valve (C1), comprising a dispenserbody (A) suited to be permanently fixed to said container (C), a valve-openingelement (B) and a cap (T) with teeth (T21) resting against said valve-openingelement (B) to cause the opening of the valve (C1); and wherein at least one tubeor duct (A1) for application of the coolant, at one end of which at least one applicatorpad or filter (S) is partially and removably inserted, is permanently built inand integral with said dispenser body (A).