THE FIRST AFFILIATED HOSPITAL OF SUN YAT-SEN UNIVERSITY;SCHOOL OF DATA AND COMPUTER SCIENCES OF SUN YAT-SEN UNIVERSITY;NATIONAL SUPERCOMPUTER CENTRE IN GUANGZHOU OF SUN YAT-SEN UNIVERSITY
发明人:
Yan Liwei,Zhu Shuang,Liu Xiaolin,Qi Jian,Zhu Qingtang,Lu Yao,Guo Yongze,Yu Sha,Lu Yutong,Zhang Xi,Du Yunfei,Lin Tao
申请号：
US201715623363
公开号：
US10147228(B2)
申请日:
2017.06.14
申请国别(地区):
美国
年份:
2018
代理人:
摘要：
The present invention relates to fields of clinical application of nerve defect repair and the medical three-dimensional (3D) printing technology, and provides an integrated visualization method for three-dimensional (3D) reconstruction of internal structure of human peripheral nerves. The method comprises the following steps: obtaining human peripheral nerves, preparing nerve specimens ex vivo by staining with an iodine preparation in combination with a freeze-drying method; scanning the pretreated peripheral nerves using Micro CT to acquire lossless two-dimensional images, and performing binarization processing to the two-dimensional images, then conducting image segmentation based on textural features to acquire images of nerve fascicles; finally, reconstructing the segmented images into a visualization model by using a supercomputer.
