FRED HUTCHINSON CANCER RESEARCH CENTER;UNIVERSITY OF WASHINGTON
发明人:
Joshua VEATCH,Stanley R. RIDDELL,Sylvia LEE
申请号:
US16638339
公开号:
US20200223899A1
申请日:
2018.08.10
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure provides binding proteins, such as TCRs, that specifically bind various tumor associated antigens (including human BRAFV600E epitope), cells expressing such antigen specific binding proteins, nucleic acids encoding the same, and compositions for use in treating diseases or disorders in which cells express BRAFV600E, such as in cancer.