MILLER, MARVIN J.;MORASKI, GARRETT;MORASKI;UNIVERSITY OF NOTRE DAME DU LAC; GARRETT
发明人:
MORASKI, GARRETT,MILLER, MARVIN J.
申请号:
EP13820038
公开号:
EP2875029A4
申请日:
2013.07.18
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The invention provides a series of 5,5-heteroaromatic compounds, syntheses thereof, compositions thereof, and methods of using such compounds and compositions. Various embodiments provide methods of killing and/or inhibiting the growth of M. tuberculosis and/or M. avium, and methods of treating, preventing, and/or ameliorating M. tuberculosis and/or M. avium infections in a subject. In various embodiments, the 5,5-heteroaromatic compound is N-(4-(4-chlorophenoxy)benzyl)-2,6-dimethylimidazo[2,1-b]thiazole-5-carboxamide.