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Precursor compound connected to solid support for manufacturing 18F radiopharmaceutical, method for manufacturing same, and application thereof
专利权人:
So-Young Chu;Hye-Rim Kwon;Jae-Hak Lee;Dae-Yoon Chi;Woon-Jung Jung;Byoung-Se Lee
发明人:
Dae-Yoon Chi,Byoung-Se Lee,Jae-Hak Lee,So-Young Chu,Woon-Jung Jung,Hye-Rim Kwon
申请号:
US13994339
公开号:
US09751844B2
申请日:
2011.12.13
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to a solid precursor in the form of an organic salt, the solid precursor having a solid support, a method for manufacturing same, and an application thereof. The solid precursor of the present invention enables omission of the [18F]fluoride refining process using additional cartridge, and the use of excessive phase-transfer catalyst, and can easily remove remaining substance after reaction through the solid support inside the precursor. The solid precursor of the present invention is very appropriate for an automated synthesis device as an all-in-one system that can carry out overall process of [18F]fluorosis reaction, when used by charging in a cartridge.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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