DCB-USA LLC;NATIONAL CHENG KUNG UNIVERSITY;NATIONAL TAIWAN UNIVERSITY;TWI BIOTECHNOLOGY, INC.
发明人:
CHUANG, WOEI-JER,FU, WEN-MEI,HUANG, YEN-LUN
申请号:
AU2010336475
公开号:
AU2010336475A1
申请日:
2010.12.22
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The invention generally relates to compositions and methods of treatment and/or prevention of angiogenesis-related eye diseases using low doses of rhodostomin variants, and in particular, low doses of a fusion protein comprising a rhodostomm variant, wherein the rhodostomin variant is conjugated with a variant of Human Serum Albumin (HSA) where the cysteine residue at position 34 of the HSA amino acid sequence has been replaced with serine.