Prosthesis for at least a portion of a bone, in particular a bone or portion thereof to which, in the natural condition, a tendon of a muscle is attached, wherein the prosthesis is manufactured of a metal or an alloy thereof and is provided with at least one area situated in the surface of the prosthesis that faces outward once the prosthesis has been placed in the body, said area being formed by a layer provided with open spaces that are connected to each other, wherein the open spaces are dimensioned for allowing the growth of bone tissue therein.