EMBODIMENTS RELATE TO SYSTEMS, METHODS AND DEVICES FOR DELIVERING A DRUG OR OTHER THERAPY TO A PATIENT WITH AN AMBULATORY INFUSION PUMP CONFIGURED TO PROVIDE A SERIES OF TOLERANCE-BUILDING STEPS LEADING UP TO A PLATEAU DELIVERY RATE. THE PLATEAU DELIVERY RATE IS MAINTAINED UNTIL THE PRESCRIBED AMOUNT OF DRUG OR THERAPY FLUID IS DELIVERED TO THE PATIENT. EMBODIMENTS OF THE INVENTION INCLUDE PROVIDING THE PATIENT OR OTHER USER WITH A MECHANISM TO DECREASE, OR STEP DOWN, THE THERAPY DELIVERY RATE IF A TOLERANCE WAS NOT ACHIEVED AT A LOWER RATE, AND PROVIDING NOTIFICATIONS PRIOR TO A STEP UP IN A DOSAGE DELIVERY RATE.
