PROBLEM TO BE SOLVED: To scale up culture, a culture tank which is a kind of metal pressure vessel is used. However, there is a problem that the risk of contamination of various bacteria is increased by mechanical ventilation, or that when the scale is changed to operate, the device must be changed according to each scale. SOLUTION: A water tank for storing water, A fine bubble generator for generating fine bubbles in the water tank, Having a gas permeable and hydrophobic film part, The organism to be cultured and the medium are stored, The culture device characterized by having a culture vessel in which the film portion is put in contact with the water in the aquarium is simple, and since the ventilation is performed through the film portion, there is no risk of contamination of bacteria due to the ventilation. [Selection diagram] Figure 1【課題】培養をスケールアップするためには、金属製の圧力容器の一種である培養槽が用いられる。しかし、機械通気により雑菌汚染される危険性が高まる、若しくは規模を変更して運転する場合は、各々の規模に合わせて装置を変えなければならないなどといった課題があった。【解決手段】水が貯留される水槽と、 前記水槽中に微細気泡を発生させる微細気泡発生装置と、 ガス透過性を有しかつ疎水性のフィルム部を有し、 被培養生物および培地が収納され、 前記フィルム部が前記水槽の水に接するように入れられる培養容器を有することを特徴とする培養装置は、簡便な上に、通気はフィルム部を通じて行うため、通気に伴う雑菌汚染の危険がない。【選択図】図１
