Synthesis of Oligonucleotide Mediated Gold Core- Silver Shell Nanoparticles

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专利权人:

Mustafa Culha

发明人:

Mustafa Culha

申请号：

US13260141

公开号：

US20120014878A1

申请日:

2009.03.23

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention relates to synthesis of oligonucleotide mediated gold core- silver shell nanoparticles and testing their SERS performance. A Raman reporter molecule and twelve-base long oligonucleotide are simultaneously attached on gold nanoparticles and a silver layer is deposited on the modified gold nanoparticles. The SERS performance of gold core- silver shell nanoparticles (CSNPs) is much greater than the CSNPs prepared without oligonucleotides and the same size non-modified gold nanoparticles after silver staining.

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