Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2

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专利权人:

AUSPEX PHARMACEUTICALS INC.

发明人:

Sommer, Andreas,Zhang, Chengzhi,Carter, John,Arthur, John,Bradbury, Margaret,Gant, Thomas,Shahbaz, Manouchehr

申请号：

NZ70537213

公开号：

NZ705372A

申请日:

2013.09.18

申请国别(地区):

NZ

年份:

2018

代理人:

摘要：

The present invention relates to extended-release pharmaceutical compositions comprising about 5 to about 30 mg of d6-tetrabenazine and a sustained-release polymer which is a polyvinyl acetate-polyvinyl pyrrolidone mixture or a poly(ethylene oxide) polymer, and uses of such compositions as medicaments to inhibit vesicular monoamine transporter 2 (VMAT2) activity in a subject for the treatment of chronic hyperkinetic movement disorders.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/