The invention provides a system for providing improved placement of magnetic compression devices at a desired target site so as to create anastomoses between tissues. The system includes a targeted member or medium configured to be placed within a hollow body of a patient. The hollow body may include, but is not limited to, the stomach, gallbladder, pancreas, duodenum, small intestine, large intestine, bowel, vasculature, including veins and arteries, or the like. The targeted member or medium is configured to provide a target site at desired anatomical location within the hollow body for formation of an anastomosis between a first portion of tissue of the hollow body at the target site and a second portion of tissue of the hollow body.