The present invention provides compositions comprising a combination of: (i) one or more B vitamins or alternative form(s), derivative(s), or salt(s) thereof, or combinations thereof, and/or source(s) thereof； and (ii) phosphatidylserine, or alternative form(s), derivative(s), or salt(s) thereof, or combinations thereof, and/or source(s) thereof； and/or lipoic acid, or alternative form(s), derlvative(s), or salt(s) thereof, or combinations thereof, and/or source(s) thereof, and/or methods of using the same combination for maintaining/improving cognitive function of adults including elderly adults and/or for maintaining/improving mood in ageing subjects and/or reducing risk markers of cardiovascular disease and/or genetic markers and/or biochemical markers associated with ageing. The compositions include, but are not limited to, dietary supplements e.g., nutritional supplements.
