The present invention provides an extracorporeal blood circulation device, which is provided with a blood purification device and a blood component regulator, and can be used safely. The present invention relates to an extracorporeal blood circulation device comprising: a blood component regulator; a blood purification device; a pump for supplying blood from a blood collection unit to the blood component regulator, a valve for supplying physiological saline, and A piping system for a pressure gauge for detecting pressure loss; a bypass piping system that bypasses the blood component regulator and supplies blood to the blood purification device; has a pressure gauge for detecting pressure loss and connects the blood component regulator and blood purification The piping system of the device; the piping system for returning the blood from the blood purification device to the blood return part, and it is equipped with a valve for recovering physiological saline and a pressure gauge for detecting pressure loss; and, it has a blood-based The pressure loss of the component regulator is used for the function of switching to the bypass piping system, and the control unit is used for the function of switching to the blood return mode based on the pressure loss of the blood purification device.本發明係提供一種體外血液循環裝置,其具備血液淨化裝置及血液成分調整器,並可安全地使用。本發明關於一種體外血液循環裝置,其具備:血液成分調整器;血液淨化裝置;具備用於將來自採血部之血液供給至血液成分調整器之幫浦、用於供給生理食鹽水之閥、及用於檢測壓力損失之壓力計的配管系統;繞過血液成分調整器並用於供給血液至血液淨化裝置的旁通配管系統;具備用於檢測壓力損失之壓力計並連接血液成分調整器及血液淨化裝置的配管系統;用於使來自血液淨化裝置之血液返回至返血部的配管系統,且其具備用於回收生理食鹽水之閥、及用於檢測壓力損失之壓力計;以及,具有基於血液成分調整器之壓力損失而用於切換至旁通配管系統之功能、及基於血液淨化裝置之壓力損失而用於切換至返血模式之功能的控制單元。